BDBM150482 US10238633, Example 156::US8987249, 156::US9713606, 156

SMILES CC1(C)OC(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1

InChI Key InChIKey=JLXZFFFCLDPPDS-YWNPBTLJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150482   

TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150482(US10238633, Example 156 | US8987249, 156 | US97136...)
Affinity DataIC50:  7.80E+3nMAssay Description:To activate the proenzyme, 5 μl procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 μL te...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM150482(US10238633, Example 156 | US8987249, 156 | US97136...)
Affinity DataIC50:  7.80E+3nMpH: 3.5 T: 2°CAssay Description:Materials: Microtiterplates (Optiplate-384 F were purchased from PerkinElmer (Prod. No. 6007270). The substrate Z-Gly-Pro-Arg-AMC was from Biomol (Pr...More data for this Ligand-Target Pair
In DepthDetails US Patent